Author's response to reviews Title: Enhancement of CURB65 score with proadrenomedullin (CURB65-A) for outcome prediction in lower respiratory tract infections: Derivation of a clinical algorithm Authors:
نویسندگان
چکیده
Werner C Albrich ([email protected]) Frank Dusemund ([email protected]) Kristina Rüegger ([email protected]) Mirjam Christ-Crain ([email protected]) Werner Zimmerli ([email protected]) Thomas Bregenzer ([email protected]) Sarosh Irani ([email protected]) Ulrich Bürgi ([email protected]) Barbara Reutlinger ([email protected]) Beat Müller ([email protected]) Philipp Schuetz ([email protected])
منابع مشابه
Enhancement of CURB65 score with proadrenomedullin (CURB65-A) for outcome prediction in lower respiratory tract infections: Derivation of a clinical algorithm
BACKGROUND Proadrenomedullin (ProADM) confers additional prognostic information to established clinical risk scores in lower respiratory tract infections (LRTI). We aimed to derive a practical algorithm combining the CURB65 score with ProADM-levels in patients with community-acquired pneumonia (CAP) and non-CAP-LRTI. METHODS We used data of 1359 patients with LRTI enrolled in a multicenter st...
متن کاملProhormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections
INTRODUCTION Measurement of prohormones representing different pathophysiological pathways could enhance risk stratification in patients with community-acquired pneumonia (CAP) and other lower respiratory tract infections (LRTI). METHODS We assessed clinical parameters and five biomarkers, the precursor levels of adrenomedullin (ADM), endothelin-1 (ET1), atrial-natriuretic peptide (ANP), anti...
متن کاملEffectiveness of Proadrenomedullin Enhanced CURB65 Score Algorithm in Patients with Community-Acquired Pneumonia in “Real Life”, an Observational Quality Control Survey
BACKGROUND An intervention trial found a trend for shorter length of stay (LOS) in patients with community-acquired pneumonia (CAP) when the CURB65 score was combined with the prognostic biomarker proadrenomedullin (ProADM) (CURB65-A). However, the efficacy and safety of CURB65-A in real life situations remains unclear. METHODS From September, 2011, until April, 2012, we performed a post-stud...
متن کاملBlood biomarkers for personalized treatment and patient management decisions in community-acquired pneumonia.
PURPOSE OF REVIEW In patients with community-acquired pneumonia (CAP), blood biomarkers can help to substantially improve individual decisions involving initiation, (de-)intensification, and cessation of antibiotics, and initial risk stratification, site-of-care assignment (outpatient versus ward versus ICU), and discharge. To illustrate these processes, this review summarizes recent findings f...
متن کاملAuthor's response to reviews Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in Title: primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671] Authors:
Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in Title: primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671]
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تاریخ انتشار 2011